The DTaP-IPV - Hib - HBV vaccination protects against diphtheria, whooping cough, tetanus, polio, Hib disease and Hepatitis B. Children receive the vaccination at 3 months, 5 months and 11 months. At 4 years and 9 years they receive a repeat vaccination.

The DTaP-IPV - Hib - HBV-vaccine in summary 

Protects against Diphtheria, whooping cough, tetanus, polio, Hib disease and Hepatitis B
Given at 3 months, 5 months and 11 months (sometimes also at 2 months; see below) 
Period of protection After the last DTaP-IPV - Hib - HBV vaccination, your child is probably protected against Hib disease and Hepatitis B for the rest of its life. Extra vaccinations against diphtheria, whooping cough, tetanus and polio are given at 4 years and 9 years (the repeat vaccination at 9 years is only for diphtheria, tetanus and polio)
Most common side effects Fever, crying, vomiting, sleepiness, diarrhoea, not drinking well and symptoms at the injection site, such as a red, swollen or painful arm

Side effects of the DTaP-IPV - Hib - HBV vaccination 

When? Most side effects occur within a day after vaccination and are gone within a couple of days.
Happens often

Fever, crying, vomiting, sleepiness, diarrhoea, not drinking well and symptoms at the injection site, such as a red, swollen or painful arm.

Happens sometimes

About 1 in 10,000 babies become suddenly unresponsive. They go limp and look very pale. This is called a collapse. It looks scary, but it generally goes away on its own within 6 to 30 minutes. It is not dangerous, and mostly occurs after the first vaccine dose in this series.
In addition, 1 in 10,000 babies may have discoloured areas on their legs. This is when all or part of the legs show red, blue or grey discolouration. The discoloured area may be puffy and warm, or cold to the touch. This also looks scary, but it generally goes away on its own within 2 hours. It very occasionally lasts as long as 3 days. It is not dangerous, and mostly occurs after the first vaccine dose in this series.
Febrile seizure: occurs within a day after vaccination (1 in 10,000 children, mostly after the vaccination at 11 months). This can happen if a fever rises very fast. The child may twitch or shake their arms and legs, or become unconscious. 

Good to know Your child cannot infect others after their DTaP-IPV - Hib - HBV vaccination. 

Nervous about side effects 

When your newborn child gets their first vaccinations, you may feel uneasy. There may be side effects. It is good to know that the vaccinations given through the National Immunisation Programme are given in many other countries as well. Studies from all those countries show that these vaccinations are safe. There are no known long-term negative effects.   

The DTaP-IPV - Hib - HBV vaccine contains parts of the bacteria that cause whooping cough, Hepatitis B, or type b Haemophilus influenzae (Hib). These parts have been made harmless and cannot make you ill. The bacteria that cause diphtheria and tetanus produce a toxic substance that makes you ill. This substance is called a toxin. The vaccine contains inactivated variants of these toxins, which cannot make you ill. The vaccine also contains modified inactivated polio viruses. These also cannot make you ill. 

The page ‘What is in vaccines?’ provides more information on what substances vaccines contain.

The page ‘How does vaccination work?’ provides information on how vaccination works.

If you are planning a trip outside the Netherlands, you usually do not need to have your child vaccinated early (before the recommended age) – unless that country has a high risk of infectious diseases. Will you be travelling abroad for a short trip or a longer period, and does your child need vaccinations? Check with the youth healthcare services (JGZ) if you need to adjust your child’s vaccination schedule. 

Do you have questions about vaccinations that you need for a trip outside the Netherlands? Consult the National Coordination Centre for Travellers Advice (LCR) website (in Dutch). The LCR website includes information on which vaccinations are advisable and where to make an appointment in your area.

If your child is ill, please contact the organisation that will give the vaccination. They can tell you if it is a good idea to get the vaccination right now. Sometimes the vaccination may be postponed for a bit. The vaccination is safe for children with reduced immunity.  

Can children with impaired immunity get the DTaP-IPV - Hib - HBV vaccination? 

The DTaP-IPV - Hib - HBV vaccination is extra important for children with reduced immunity as a result of disease or medication. The vaccination is safe for children with impaired immunity, but it may be less effective. Children with these health conditions always have their case supervised by a treating paediatrician, who can provide more information.